Endocrine Abstracts

Introduction: The parathyroid gland is made up of principal cells and oxyphilic cells, surrounded by stroma, whose main component is adipose tissue, which accounts for 25% of the content of the parathyroid in adults. In parathyroid adenomas, prominent parathyroid cellularity can be observed, with a very marked decrease in the stroma. Parathyroid lipoadenoma is a rare variant of parathyroid adenoma, characterized by hyperfunctioning parathyroid cells in an abundant fatty stroma...

Introduction: Insulinomas are pancreatic neuroendocrine tumors (PNET), characterized by insulin hypersecretion syndrome with the development of hypoglycemia. The incidence of the tumor is 3-10 cases per million inhabitants. The average age of onset is 40-50 years old, being more frequent in women. Case Reports: We present a clinical case of a patient with CREST syndrome and difficult-to-control hypoglycemia. Female patient, 81 years old, with a history o...

Introduction: New treatments of diabetes, such as dapagliflozin, improve global metabolic status beyond glycemic control.Aim: To evaluate tolerance to dapagliflozin and its effects on metabolic control in type 2 diabetes and obese patients attended in endocrinology offices.Material and method: A prospective study of patients with type 2 diabetes and obesity. In an intra-subject analysis, clinical and analytical data were evaluated ...

Objective: To evaluate continuous subcutaneous insulin infusion (CSII) in type 1 diabetes using the analysis of epidemiological variables, treatment indications, metabolic results, acute and chronic complications and causes for therapy suspension.Methods: A retrospective descriptive study of patients with type 1 diabetes treated with CSII therapy in our institution.Results: A total of 49 type 1 diabetic patients who had been treate...

Objective: To evaluate the efficacy of liraglutide, a new glucagon-like peptide 1 analogue, on glycaemic control, body weight, blood pressure and lipid profile in obese patients with type 2 diabetes mellitus (T2DM).Material and methods: Patients attending a tertiary Endocrinology Unit who were prescribed liraglutide (January 2013–December 2013) and assessed both at baseline and first post-initiation visit were included in the analysis. The primary e...

Introduction: Many studies showed that H. pylori infection could be an independent predictor for insulin resistance and could regulate metabolism and body weight.Aim: To evaluate changes in metabolism induced by an oral glucose tolerance test (OGTT) before and after antibiotic eradication treatment in patients colonized by H. pylori.Materials and method: Prospective case-controlled study with a sample of patients colonized by H. py...

Objective: The aim of this study is to evaluate the effectiveness of once-weekly exenatide on metabolic control, weight, blood pressure, and lipid profile in obese patients with type 2 diabetes (T2DM), and to assess possible predictive factors of response.Material and methods: Retrospective observational study, conducted with adult obese (BMI ≥30 kg/m2) T2DM subjects that had been initiated once-weekly exenatide following routine clinica...

Aim: Evaluation of hypocortisolism and replacement treatment after transsphenoidal surgery pituitary adenomas and subsequent follow-up in Endocrinology offices.Material and methodWe conducted a retrospective intra-subject study of patients with pituitary adenomas who were undergone surgery. Clinical and analytical data were evaluated at baseline and after surgery between 2012–2018.Results: 30 patients (...

Introduction: H. pylori infection has been related with diseases such as type 2 diabetes and metabolic syndrome.Objective: To evaluate changes in carbohydrates metabolism, lipid profile and intake regulating hormones induced by 75 g oral glucose tolerance test (OGTT), before and after antibiotic eradication treatment in patients colonized by H. pylori.Materials and methods: A prospective study of 40 non-diabetics patients were perf...

Introduction: New diabetes treatments, such as lixisenatide, improve global metabolic status beyond glycemic control.Aim: To evaluate lixisenatide effects on liver function, lipids and blood pressure levels in type 2 diabetes and obese patients attended in endocrinology offices.Material and method: This is a prospective study with a sample of 106 patients with type 2 diabetes and obesity. In an intra-subject analysis, clinical and ...